BibTex format
@article{Haque:2023:10.1016/j.bmc.2023.117311,
author = {Haque, M and Flack, T and Singh, R and Wall, A and Vieira, de Castro G and Jiang, L and White, A and Barnard, A},
doi = {10.1016/j.bmc.2023.117311},
journal = {Bioorganic and Medicinal Chemistry},
title = {Aromatic oligoesters as novel helix mimetic scaffolds},
url = {http://dx.doi.org/10.1016/j.bmc.2023.117311},
volume = {87},
year = {2023}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - The design, synthesis, and conformational analysis of a novel aromatic oligoester helix mimetic scaffold is reported. A range of amino acid-type side-chain functionality can be readily incorporated into monomer building blocks over three facile synthetic steps. Analysis of representative dimers revealed a stable conformer capable of effective mimicry of a canonical α-helix and the scaffold was found to be surprisingly stable to degradation in aqueous solutions at acidic and neutral pH.
AU - Haque,M
AU - Flack,T
AU - Singh,R
AU - Wall,A
AU - Vieira,de Castro G
AU - Jiang,L
AU - White,A
AU - Barnard,A
DO - 10.1016/j.bmc.2023.117311
PY - 2023///
SN - 0968-0896
TI - Aromatic oligoesters as novel helix mimetic scaffolds
T2 - Bioorganic and Medicinal Chemistry
UR - http://dx.doi.org/10.1016/j.bmc.2023.117311
UR - http://hdl.handle.net/10044/1/104264
VL - 87
ER -