@article{Beckwith:2022:10.1016/j.semnephrol.2022.04.008,
author = {Beckwith, H and Lightstone, L and McAdoo, S},
doi = {10.1016/j.semnephrol.2022.04.008},
journal = {Seminars in Nephrology},
pages = {185--196},
title = {Sex and gender in glomerular disease.},
url = {http://dx.doi.org/10.1016/j.semnephrol.2022.04.008},
volume = {42},
year = {2022}
}

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TY  - JOUR
AB  - There is increasing understanding that a multifaceted interplay of sex-dependent genetic and immune dysregulation underpins the development of glomerular disorders. Regional and ethnic variations in glomerular disease incidence make delineating the effects of sex and gender on disease pathophysiology more complex, but there is a marked paucity of research in this area. This review article presents a summary of the current understanding of sex and gender in glomerular disease, highlighting the broader effects of sex and gender on autoimmunity, clinical presentations, and pathophysiology of individual glomerular diseases, as well as exploring sex, gender, and glomerular disease within a wider socioenvironmental context. It is important to specifically consider the effects of sex and gender when presenting and analyzing clinical and scientific studies on glomerular disease. Failure to do so risks promoting disparities within health care provision, neglecting opportunities to identify sex-specific biomarkers, and potentially hindering the development of sex-specific therapies.
AU  - Beckwith,H
AU  - Lightstone,L
AU  - McAdoo,S
DO  - 10.1016/j.semnephrol.2022.04.008
EP  - 196
PY  - 2022///
SN  - 0270-9295
SP  - 185
TI  - Sex and gender in glomerular disease.
T2  - Seminars in Nephrology
UR  - http://dx.doi.org/10.1016/j.semnephrol.2022.04.008
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35718365
UR  - https://www.seminarsinnephrology.org/article/S0270-9295(22)00016-X/fulltext
UR  - http://hdl.handle.net/10044/1/98499
VL  - 42
ER  - 

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