Citation

BibTex format

@article{Kench:2020:10.26434/chemrxiv.13249643.v1,
author = {Kench, T and Summers, PA and Kuimova, MK and Lewis, J and Vilar, R},
doi = {10.26434/chemrxiv.13249643.v1},
title = {Rotaxanes as Cages to Control DNA Binding, Cytotoxicity and Cellular Uptake of a Small Molecule},
url = {http://dx.doi.org/10.26434/chemrxiv.13249643.v1},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - <jats:p>In this paper we report a unique approach to control the DNA interactions, cellular uptake and cellular localisation of a small molecule. We have designed rotaxanes that include a luminescent DNA binder, a macrocycle that modulates the DNA binding and a stopper that can be cleaved by either light or the activity of an enzyme.</jats:p>
AU - Kench,T
AU - Summers,PA
AU - Kuimova,MK
AU - Lewis,J
AU - Vilar,R
DO - 10.26434/chemrxiv.13249643.v1
PY - 2020///
TI - Rotaxanes as Cages to Control DNA Binding, Cytotoxicity and Cellular Uptake of a Small Molecule
UR - http://dx.doi.org/10.26434/chemrxiv.13249643.v1
ER -

Contact:

Professor Ramon Vilar
Department of Chemistry
Imperial College London
Molecular Sciences Research Hub
White City Campus
82 Wood Lane
London W12 0BZ
 
Email: r.vilar@imperial.ac.uk
Tel: +44(0)20 7594 1967