In this section
@article{Moreddu:2021:10.1002/smll.202102008,
author = {Moreddu, R and Nasrollahi, V and Kassanos, P and Dimov, S and Vigolo, D and Yetisen, AK},
doi = {10.1002/smll.202102008},
journal = {Small},
title = {Lab-on-a-contact lens platforms fabricated by multi-axis femtosecond laser ablation},
url = {http://dx.doi.org/10.1002/smll.202102008},
volume = {17},
year = {2021}
}
TY - JOUR
AB - Contact lens sensing platforms have drawn interest in the last decade for the possibility of providing a sterile, fully integrated ocular screening technology. However, designing scalable and rapid contact lens processing methods while keeping a high resolution is still an unsolved challenge. In this article, femtosecond laser writing is employed as a rapid and precise procedure to engrave microfluidic networks into commercial contact lenses. Functional microfluidic components such as flow valves, resistors, multi-inlet geometries, and splitters are produced using a bespoke seven-axis femtosecond laser system, yielding a resolution of 80 µm. The ablation process and the tear flow within microfluidic structures is evaluated both experimentally and computationally using finite element modeling. Flow velocity drops of the 8.3%, 20.8%, and 29% were observed in valves with enlargements of the 100%, 200%, and 300%, respectively. Resistors yielded flow rate drops of 20.8%, 33%, and 50% in the small, medium, and large configurations, respectively. Two applications were introduced, namely a tear volume sensor and a tear uric acid sensor (sensitivity 16 mg L−1), which are both painless alternatives to current methods and provide reduced contamination risks of tear samples.
AU - Moreddu,R
AU - Nasrollahi,V
AU - Kassanos,P
AU - Dimov,S
AU - Vigolo,D
AU - Yetisen,AK
DO - 10.1002/smll.202102008
PY - 2021///
SN - 1613-6810
TI - Lab-on-a-contact lens platforms fabricated by multi-axis femtosecond laser ablation
T2 - Small
UR - http://dx.doi.org/10.1002/smll.202102008
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000686174200001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - https://onlinelibrary.wiley.com/doi/10.1002/smll.202102008
VL - 17
ER -