The MET-FINGER study is a randomised controlled trial conducted in the UK (Imperial College London), Finland, and Sweden. The study is sponsored by Imperial College London. In MET-FINGER, we aim to see whether a combination of healthy lifestyle changes and a drug used to treat diabetes (metformin) may help reduce the risk of dementia.

The study is open and is looking to include about 600 people overall at the three sites. Half of the volunteers will be assigned to a “Self-guided” and half to a “Structured” lifestyle programme. Within the Structured lifestyle programme, volunteers who qualify for the treatment with metformin will be also assigned to additionally receive either metformin or placebo.