Project Title: Developing closed-loop control brain stimulation to treat Alzheimer’s disease
Supervisor: Dr Nir Grossman
Location: Level 7, Sir Michael Uren Hub, White City Campus, 86 Wood Lane, W12 0BZ
About Me
I am a Clinical PhD Fellow in the Grossman Lab at the Department of Brain Sciences within the UK Dementia Research Institute. My project focuses on applying Temporal Interference (TI) stimulation to patients with Mild Cognitive Impairment and Alzheimer’s Disease. I am currently leading a clinical trial to investigate the effects of TI stimulation on cognitive performance and concurrently recorded EEG. A key goal is to identify EEG features that could inform the development of a closed-loop stimulation system, paving the way for a novel therapy for this patient group.
During my clinical training in psychiatry, I became increasingly aware of the urgent need for new treatments for brain disorders. TI stimulation, and the broader goal of ‘precision electronic medicine’, presents an exciting opportunity to deepen our understanding of the brain and develop impactful therapies for a wide range of conditions.
Outside of my research, I enjoy running, photography, music and film. I also lead the development of a digital mental health app designed to support individuals on the waiting list for cognitive behavioural therapy (CBT) and enhance engagement with psychological services.
Qualifications
MRCPsych, Royal College of Psychiatrists - 2023
MPhil Translational Biomedical Research, University of Cambridge - 2021
MBBS Medicine, University of East Anglia - 2017
Research Interests
Closed-loop neuromodulation, ML for EEG classification, Computational Neuroscience
Contact Details
Email: stw23@ic.ac.uk
LinkedIn: simon-williamson-2bb2aa290