We use light to develop advanced diagnostic tools, wearable sensors, and microscale robots for studying diseases and enabling minimally invasive treatments.

Head of Group

Dr Alex Thompson

Office B411, Bessemer Building,
South Kensington Campus

⇒ X @_Thompson_Alex

 

 

What we do

We use photonics to develop new technologies for medicine and to study the pathophysiology of disease. This includes new and improved diagnostic tools as well as microscale robotic devices for therapeutic applications. We use a variety of optical techniques for this purpose such as fluorescence, Raman and diffuse reflectance spectroscopy, as well as microscopy and interferometry. We develop devices ranging from wearable sensors and fibre-optic probes for minimally invasive diagnostics through to microscale robots for cellular-scale manipulation and therapy.

Why it is important?

Our research has a number of potential clinical applications including improved monitoring of clinical therapies and interventions (e.g. in inflammatory bowel disease and malnutrition), early diagnosis of infection, and even margin mapping in tumour resection surgery.

How can it benefit patients?

The devices we are developing can potentially provide less invasive and lower cost diagnostics. In turn, this may facilitate patient benefits including earlier diagnosis, earlier identification of relapse (e.g. in therapy response monitoring applications), more widespread deployment and more comfortable patient experiences (e.g. through use of less invasive probes and sensors).

Meet the team

Dr Nilanjan Mandal

Dr Nilanjan Mandal
Research Associate in Optical Sensing for LMICs

Mr Zeyu Wang

Mr Zeyu Wang
Research Postgraduate

Citation

BibTex format

@inproceedings{Power:2017:10.1109/MARSS.2017.8001946,
author = {Power, M and Seneci, CA and Thompson, AJ and Yang, GZ},
doi = {10.1109/MARSS.2017.8001946},
publisher = {IEEE},
title = {Modelling & characterization of a compliant tethered microgripper for microsurgical applications},
url = {http://dx.doi.org/10.1109/MARSS.2017.8001946},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - CPAPER
AB - The development of microscale surgical tools could pave the way for truly minimally invasive microsurgical procedures. This work demonstrates the application of direct laser writing (DLW) using two-photon polymerization (TPP), a rapid prototyping microfabrication technique, to create a tethered, passively actuated three-dimensional gripper with potential applications in microbiopsy. A microgripper design was devised, modelled and optimized. The gripper was then fabricated and characterized for validation of the theoretical model. The results demonstrate that modelling the behavior of compliant microtools provides a useful approximation for the observed trends and, thus, can be utilized in the design of TPP tools. Future work on the incorporation of viscoelastic material into the model will further improve agreement between the predicted and experimental performance.
AU - Power,M
AU - Seneci,CA
AU - Thompson,AJ
AU - Yang,GZ
DO - 10.1109/MARSS.2017.8001946
PB - IEEE
PY - 2017///
TI - Modelling & characterization of a compliant tethered microgripper for microsurgical applications
UR - http://dx.doi.org/10.1109/MARSS.2017.8001946
UR - http://hdl.handle.net/10044/1/52201
ER -

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The Hamlyn Centre
Bessemer Building
South Kensington Campus
Imperial College
London, SW7 2AZ
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