In this section
The Micro-Nano Innovation Lab ("mini lab") investigates multidisciplinary approaches to develop new intelligent sensing and robotic strategies in micro/nano scales.
The Micro-Nano Innovation Lab ("mini lab") investigates multidisciplinary approaches to develop new intelligent sensing and robotic strategies in micro/nano scales. We study nanotechnology, light-matter interactions, micro-particle dynamics, microscale fluid dynamics, and bioengineering to reach our goal. The research involves the design and manufacture of micro/nano systems for diagnostics (e.g. infections, cancer, neurodegenerative diseases) and microscopic therapies/surgeries (e.g. localised drug delivery, novel minimally invasive procedures).
Timely identification of illnesses, less intrusive interventions, and precise/personalised treatments in challenging areas within our bodies, like narrow blood vessels, are essential technologies for improved healthcare management. The foundation for empowering these technologies lies in the development of devices capable of sensitively detecting disruptions in microenvironments that impact normal physiology and of precisely addressing these issues via targeted drug delivery, surgery, etc. at the cellular and molecular levels (micro/nano scales). Understanding the pathophysiology and engineering of the designs and functionalities of such devices accordingly is, thus, vital to enhancing current medical technology. Also, this has the potential to drive the development of advanced medical micro-robots with integrated sensing and therapeutic capabilities, offering new opportunities for future advancements in healthcare.
Early detection of diseases followed by minimally invasive, targeted and personalised therapy can have evident advantages for patients in terms of prognosis, health management, and economic implications. First, it can reduce excessive physical and biochemical alterations to the microenvironments, e.g., scarring after resection, antimicrobial resistance after antibiotics administration, etc., offering a better prognosis with fewer side effects. Micro/nanodevices can also be engineered to be implantable, enabling long-term health monitoring and treatment. Finally, the localised and precise manner of the technology allows efficient planning of the optimal procedures and accurate dosage, resulting in reduced cost.
Mr Seungyeop Kang
Research Postgraduate
Dr Jang Ah Kim
Lecturer
@inbook{Saini:2023:10.1007/978-981-19-7188-4_38,
author = {Saini, N and Pandey, P and Wankar, S and Shirolkar, M and Kulkarni, AA and Kim, JA and Kim, T and Kulkarni, A},
booktitle = {Materials Horizons: From Nature to Nanomaterials},
doi = {10.1007/978-981-19-7188-4_38},
pages = {1067--1089},
title = {Carbon Nanomaterial-Based Biosensors: A Forthcoming Future for Clinical Diagnostics},
url = {http://dx.doi.org/10.1007/978-981-19-7188-4_38},
year = {2023}
}
TY - CHAP
AB - Advancements in various scientific domains such as genetics, bioinformatics, immunology, medicines, and computational analysis have a colossal impact for the evolution of diagnostics/sensing platforms. These advances contribute towards enhanced reliability, economic, quicker, and patient centric/compliant sensing platforms; for ultrasensitive diagnosis of non-communicable diseases (cancer, cardiovascular ailments are few). According to WHO report, comprehensive containment/control of non-communicable diseases must be executed effectively. The key to achieve this would be enhanced accessibility to early diagnosis. The attributes of an ideal diagnostics set apart by WHO are affordable, sensitive, user-friendly, rapid, and robust use, equipment free, delivered to the needy. These qualities are easier to meet with biosensor devices. With these significant qualities and miniaturization, demand of biosensor production has ramped up during the last decade. As biosensors provide minimal invasion, thus are suitable to enhance successful treatment and patient survival. Conversely, carbon element possesses diverse properties at nanoscale, rendering it expedient for fabrication into biosensors, and thus, the carbon nanomaterials such as graphene, carbon nanotube are used as elite nanomaterials in healthcare-associated biosensors. In this chapter, we described the biosensors as physical biosensors with primary focus on optical biosensors such as surface plasmon resonance-based biosensors and surface-enhanced Raman scattering-based biosensors and chemical biosensors with electrochemical biosensors in details and their role in disease identification, over the past years. The primary impetus of this chapter is to focus upon carbon nanomaterial-based optical and electrochemical biosensors. In addition, the role of carbon nanomaterial in future generation of biosensors evolution is described briefly.
AU - Saini,N
AU - Pandey,P
AU - Wankar,S
AU - Shirolkar,M
AU - Kulkarni,AA
AU - Kim,JA
AU - Kim,T
AU - Kulkarni,A
DO - 10.1007/978-981-19-7188-4_38
EP - 1089
PY - 2023///
SP - 1067
TI - Carbon Nanomaterial-Based Biosensors: A Forthcoming Future for Clinical Diagnostics
T1 - Materials Horizons: From Nature to Nanomaterials
UR - http://dx.doi.org/10.1007/978-981-19-7188-4_38
ER -
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