.jpg)
Biomedical Research (Molecular Basis of Human Disease)
Train for a career in biomedical research and specialise in molecular mechanisms and structural biology.
Receive broad training for a career in biomedical research and specialise in molecular mechanisms and structural biology
Learn how to investigate disease pathways and explore potential therapeutic interventions on pressing human diseases
Complete two five-month research projects and examine cutting-edge developments in the field
Course key facts
-
Qualification
-
MRes
-
-
Duration
1 year
-
Start date
September 2025
-
Study mode
Full-time
-
Fees
£20,600 Home
£45,000 Overseas
-
Delivered by
-
Location
-
South Kensington
-
Course overview
Build multidisciplinary skills in biomedical research on this Master's course, specialising in molecular mechanisms and structural biology.
You'll explore fundamental disease mechanisms and the scientific methodology used to unravel these mechanisms.
Broad training is provided in a range of biomedical research areas. These include structural molecular biology, biochemistry and biophysics, cell biology and clinical/pharmaceutical applications.
You'll build transferable skills through a programme of grant writing, technical workshops and journal clubs. You'll also investigate disease pathways and potential therapeutic interventions on pressing human diseases.
Two extensive research projects provide an opportunity to apply your expertise to areas of interest within this specialism.
Choose your stream
You have the option of choosing our general biomedical research stream, or one of seven specialisms. All of our biomedical research streams have the same course structure and each stream has its own tailored set of projects alongside a core programme of lectures, seminars and practical classes.
You should consider which stream is right for you according to your career aims and background. If an offer of admission is made, it will correspond to a specific stream. Switching streams is not possible once you have commenced your studies.
- General Biomedical Research
- Anaesthetics, Pain Medicine and Intensive Care
- Bacterial Pathogenesis and Infection
- Data Science
- Epidemiology, Evolution and Control of Infectious Diseases
- Microbiome in Health and Disease
- Molecular Basis of Human Disease (this stream)
- Respiratory and Cardiovascular Science
Is this stream for you?
This stream is for students with a biochemical or biophysical background interested in pursuing further education in a medically relevant area, and those with a biomedical background interested in understanding fundamental mechanisms behind disease processes.
This stream is delivered by the Department of Metabolism, Digestion and Reproduction in collaboration with the Department of Infectious Disease.
Structure
This page is updated regularly to reflect the latest version of the curriculum. However, this information is subject to change.
Find out more about potential course changes.
Please note: it may not always be possible to take specific combinations of modules due to timetabling conflicts. For confirmation, please check with the relevant department.
You’ll take all of these core modules.
Core modules
Compose a grant proposal, appropriate for submission to an academic funding body.
This will correspond to your research project(s).
You'll carry out two mini research projects, exploring some of the most technologically advanced approaches currently being applied to biomedical research.
You have a wide range of research projects available to you.
The projects available to you are determined by your chosen stream.
You can also choose projects from other streams, though you will only have priority within your own stream.
Example projects
- How does proteostasis restrict toxic protein aggregates from damaging the cell?
- The role of Mannose-6-phosphate receptor (M6PR) in human pancreatic β-cells
- Investigating the role of CD63 in human adipose stem cells
- How the bacterial type II secretion system powers toxin release
- The Tight adherence molecular machine builds pili and drives bacterial pathogenesis
- Novel neuromodulators from the gut microbiome
- Biosensor screening using a bacterial synthetic memory circuit
- Spatial biosensor development for the inflammatory biomarker sialic acid
- Using wildDISCO to characterise disruption of sleep-wake cycles in Alzheimer's disease
- Investigating the impact of genomic diversity on cell wall chemistry in Aspergillus fumigatus
See a full list of example Biomedical research projects on the Department of Metabolism, Digestion and Reproduction web pages.
Teaching and assessment
Teaching and learning methods
-
Demonstrations and seminars
-
Workshops
-
Computing labs
-
Journal clubs
-
Virtual learning environment
-
Tutorials
-
Lab-based learning
-
Facility Tours
-
Lectures
-
Debates
Balance of assessment
Key
- Grant writing exercise
- Research projects
- 10% Grant writing exercise
- 90% Research projects
Assessment methods
-
Laboratory-based research
-
Computer-based research
-
Oral presentation
-
Poster presentation
-
Research reports
-
Oral assessment
Entry requirements
We consider all applicants on an individual basis, welcoming students from all over the world.
How to apply
Apply online
You can submit one application form per year of entry. You can choose up to two courses.
In our application system My Imperial, you will need to choose Biomedical Research (MRes 1YFT) in the Programme selection search. After this, you will be asked to choose the stream you wish to be considered for.
The Department's Biomedical Research Admissions FAQ provides more details about applying for the course.
There is no application fee for MRes courses, Postgraduate Certificates, Postgraduate Diplomas, or courses such as PhDs and EngDs.
If you are applying for a taught Master’s course, you will need to pay an application fee before submitting your application.
The fee applies per application and not per course.
- £80 for all taught Master's applications, excluding those to the Imperial College Business School.
- £100 for all MSc applications to the Imperial College Business School.
- £150 for all MBA applications to the Imperial College Business School.
If you are facing financial hardship and are unable to pay the application fee, we encourage you to apply for our application fee waiver.
Find out more about how to apply for a Master's course, including references and personal statements.
An ATAS certificate is not required for students applying for this course.
Tuition fees
Home fee
2025 entry
£20,600
You should expect and budget for your fees to increase each year.
Your fee is based on the year you enter the university, not your year of study. This means that if you repeat a year or resume your studies after an interruption, your fees will only increase by the amount linked to inflation.
Find out more about our tuition fees payment terms, including how inflationary increases are applied to your tuition fees in subsequent years of study.
Whether you pay the Home or Overseas fee depends on your fee status. This is assessed based on UK Government legislation and includes things like where you live and your nationality or residency status. Find out how we assess your fee status.
If you're a UK national, or EU national with settled or pre-settled status under the EU Settlement Scheme, you may be able to apply for a Postgraduate Master’s Loan from the UK government, if you meet certain criteria.
For courses starting on or after 1 August 2024, the maximum amount is £12,471.
The loan is not means-tested and you can choose whether to put it towards your tuition fees or living costs.
We offer a range of scholarships for students to support you through your studies.
See what opportunities you may be eligible for on our dedicated Scholarships search tool.
Overseas fee
2025 entry
£45,000
You should expect and budget for your fees to increase each year.
Your fee is based on the year you enter the university, not your year of study. This means that if you repeat a year or resume your studies after an interruption, your fees will only increase by the amount linked to inflation.
Find out more about our tuition fees payment terms, including how inflationary increases are applied to your tuition fees in subsequent years of study.
Whether you pay the Home or Overseas fee depends on your fee status. This is assessed based on UK Government legislation and includes things like where you live and your nationality or residency status. Find out how we assess your fee status.
If you're a UK national, or EU national with settled or pre-settled status under the EU Settlement Scheme, you may be able to apply for a Postgraduate Master’s Loan from the UK government, if you meet certain criteria.
For courses starting on or after 1 August 2024, the maximum amount is £12,471.
The loan is not means-tested and you can choose whether to put it towards your tuition fees or living costs.
Scholarships
The Dean’s Master’s Scholarships
Value per award
- £10,000
Who it's for
- All students applying to study a Faculty of Medicine Master’s course
The Dr Jean Alero Thomas Scholarships
Value per award
- Partial or full tuition fee at the Home rate
Who it's for
- All students applying to study a Faculty of Medicine lab-based Master’s course
Department of Metabolism, Digestion and Reproduction Bursaries
Value per award
- £2,000 (full-time) or £1,000 per year (part-time, two-years)
Who it's for
- Offer holders for the department's MSc/MRes courses
How will studying at Imperial help my career?
Strengthen your career prospects as aspiring Anaesthetists and Intensive Care physicians.
Cultivate a robust network within an inclusive Division, fostering valuable connections with academics and clinicians.
Participate in Departmental Research symposia, offering exposure, critical appraisal skills, expert engagement, and staying updated in the field.
-(1).svg){kind=icon}
Develop key academic skills to support your progress to PhD or medical school.
Develop essential soft skills, such as communication, teamwork, and adaptability, crucial for success in professional healthcare environments.
Get support with grant applications and publication of research findings, enriching academic and professional portfolios.
.svg){kind=icon}
Participate in Departmental Research symposia, offering exposure, critical appraisal skills, expert engagement, and staying updated in the field.
Further links
Contact the department
Email: biomedical.researchmres@imperial.ac.uk
Course Director: Professor Tim Ebbels
Course Deputy Director: Dr Elizabeth Want
Stream Organiser: Dr Harry Low
Visit the Department of Metabolism, Digestion, and Reproduction website.
/fit-in/1440x9999999/prod01/channel_3/media/study---restricted-images/17_314-Imperial-NHS-StM-Ham-210.jpg)
Our students
Meet Biomedical Research students and see what they have to say about their studies.
You can also read more about our student achievements, including funding, publications and academic prizes.
/fit-in/1440x9999999/prod01/channel_3/media/study---restricted-images/course-pages/postgraduate/medicine---metabolism-digestion-and-reproduction/Applied-Genomics.jpg)
Register your interest
Stay up to date on news, events, scholarship opportunities and information related to this course.
/fit-in/1440x9999999/prod01/channel_3/media/study---restricted-images/Newsletter.jpg)
Events, tasters and talks
Meet us and find out more about studying at Imperial.
/fit-in/1440x9999999/prod01/channel_3/media/study---restricted-images/UG---Events.jpg)
Terms and conditions
There are some important pieces of information you should be aware of when applying to Imperial. These include key information about your tuition fees, funding, visas, accommodation and more.
You can find further information about your course, including degree classifications, regulations, progression and awards in the programme specification for your course.
Programme specifications