BibTex format
@article{Citarella:2024:10.1016/j.heliyon.2024.e29591,
author = {Citarella, BW and Kartsonaki, C and Ibáñez-Prada, ED and Gonçalves, BP and Baruch, J and Escher, M and Pritchard, MG and Wei, J and Philippy, F and Dagens, A and Hall, M and Lee, J and Kutsogiannis, DJ and Wils, E-J and Fernandes, MA and Tirupakuzhi, Vijayaraghavan BK and Panda, PK and Martin-Loeches, I and Ohshimo, S and Fatoni, AZ and Horby, P and Dunning, J and Rello, J and Merson, L and Rojek, A and Vaillant, M and Olliaro, P and Reyes, LF and ISARIC, Clinical Characterisation Group},
doi = {10.1016/j.heliyon.2024.e29591},
journal = {Heliyon},
title = {Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms.},
url = {http://dx.doi.org/10.1016/j.heliyon.2024.e29591},
volume = {10},
year = {2024}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - BACKGROUND: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms (NRS) and respiratory symptoms (RS) at hospital admission. METHODS: This study describes clinical features, physiological parameters, and outcomes of hospitalised COVID-19 patients, stratified by the presence or absence of respiratory symptoms at hospital admission. RS patients had one or more of: cough, shortness of breath, sore throat, runny nose or wheezing; while NRS patients did not. RESULTS: Of 178,640 patients in the study, 86.4 % presented with RS, while 13.6 % had NRS. NRS patients were older (median age: NRS: 74 vs RS: 65) and less likely to be admitted to the ICU (NRS: 36.7 % vs RS: 37.5 %). NRS patients had a higher crude in-hospital case-fatality ratio (NRS 41.1 % vs. RS 32.0 %), but a lower risk of death after adjusting for confounders (HR 0.88 [0.83-0.93]). CONCLUSION: Approximately one in seven COVID-19 patients presented at hospital admission without respiratory symptoms. These patients were older, had lower ICU admission rates, and had a lower risk of in-hospital mortality after adjusting for confounders.
AU - Citarella,BW
AU - Kartsonaki,C
AU - Ibáñez-Prada,ED
AU - Gonçalves,BP
AU - Baruch,J
AU - Escher,M
AU - Pritchard,MG
AU - Wei,J
AU - Philippy,F
AU - Dagens,A
AU - Hall,M
AU - Lee,J
AU - Kutsogiannis,DJ
AU - Wils,E-J
AU - Fernandes,MA
AU - Tirupakuzhi,Vijayaraghavan BK
AU - Panda,PK
AU - Martin-Loeches,I
AU - Ohshimo,S
AU - Fatoni,AZ
AU - Horby,P
AU - Dunning,J
AU - Rello,J
AU - Merson,L
AU - Rojek,A
AU - Vaillant,M
AU - Olliaro,P
AU - Reyes,LF
AU - ISARIC,Clinical Characterisation Group
DO - 10.1016/j.heliyon.2024.e29591
PY - 2024///
SN - 2405-8440
TI - Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms.
T2 - Heliyon
UR - http://dx.doi.org/10.1016/j.heliyon.2024.e29591
UR - https://www.ncbi.nlm.nih.gov/pubmed/38779000
VL - 10
ER -