BibTex format
@article{Mengistu:2024:10.1186/s13071-024-06422-2,
author = {Mengistu, B and Liyew, EF and Chernet, M and Tasew, G and Maddren, R and Collyer, B and Anjulo, U and Tamiru, A and Forbes, K and Mehari, Z and Deribe, K and Yadeta, T and Salasibew, M and Tollera, G and Anderson, R},
doi = {10.1186/s13071-024-06422-2},
journal = {Parasit Vectors},
title = {Soil-transmitted helminth (STH) infections in the Wolaita zone in Southern Ethiopia: mid-stage evaluation of the Geshiyaro project and progress towards the interruption of transmission.},
url = {http://dx.doi.org/10.1186/s13071-024-06422-2},
volume = {17},
year = {2024}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - BACKGROUND: This paper documents changes in the prevalence and intensity of soil-transmitted helminth (STH) infections in the Geshiyaro project in the Wolaita zone of Southern Ethiopia. METHODS: The Geshiyaro project comprises three intervention arms. Arm 1 is subdivided into the Arm 1 pilot (one district) and Arm 1 (four other districts), both receiving integrated community-wide mass drug administration MDA (cMDA) with intensive water, sanitation, and hygiene (WaSH) interventions. Arm 2 involves 18 districts with cMDA interventions plus the existing government-led One WaSH program, while Arm 3 serves as a control with school-based MDA (sMDA) interventions plus the existing government-led One WaSH program in three districts. The study is designed as a cohort investigation over time, with the establishment of longitudinal sentinel sites where infection levels are assessed annually. A total of 45 longitudinal parasitological surveillance sentinel sites are being used across all three intervention arms to monitor STH prevalence and intensity of infection. From each of the 45 sentinel sites, 150 individuals were randomly selected, stratified by age and gender. The t-test and analysis of variance (ANOVA) were employed to compare infection prevalence and intensity across the three study arms over time. RESULTS: The prevalence of STH decreased significantly from 34.5% (30.6%, 38.5%) in 2019 to 10.6% (8.3%, 13.4%) in 2022/2023 (df = 1, P < 0.0001) in the Arm 1 pilot, from 27.4% (25.2%, 29.7%) in 2020 to 5.5% (4.4%, 6.7%) in 2023 (df = 1, P < 0.0001) in Arm 1, from 23% (21.3%, 24.8%) in 2020 to 4.5% (3.7%, 5.3%) in 2023 (df = 1, P < 0.001) in Arm 2, and from 49.6% (47.4%, 51.7%) in 2021 to 26.1% in 2023 (df = 1, P < 0.0001) in Arm 3. The relative reduction in the prevalence of any STH was the highest in the arms employing cMDA, namely Arm 2, with a decr
AU - Mengistu,B
AU - Liyew,EF
AU - Chernet,M
AU - Tasew,G
AU - Maddren,R
AU - Collyer,B
AU - Anjulo,U
AU - Tamiru,A
AU - Forbes,K
AU - Mehari,Z
AU - Deribe,K
AU - Yadeta,T
AU - Salasibew,M
AU - Tollera,G
AU - Anderson,R
DO - 10.1186/s13071-024-06422-2
PY - 2024///
TI - Soil-transmitted helminth (STH) infections in the Wolaita zone in Southern Ethiopia: mid-stage evaluation of the Geshiyaro project and progress towards the interruption of transmission.
T2 - Parasit Vectors
UR - http://dx.doi.org/10.1186/s13071-024-06422-2
UR - https://www.ncbi.nlm.nih.gov/pubmed/39169385
VL - 17
ER -