About us
Imperial College London has international reputation for research in perinatal neurology and brain imaging, spanning over several decades. We lead one of the largest clinical research programs in neonatal encephalopathy in the world. Neonatal encephalopathy, or brain injury related to 'birth asphyxia' is a devastating condition due to a presumed lack of oxygen and blood flow to the fetal brain, possibly around the time of birth. Pioneering research undertaken in the unit, along with many other researchers and collaborators in the UK and worldwide led to the establishment of brain cooling as the first effective therapy for neonatal encephalopathy. However, despite cooling therapy, almost half of the babies born with neonatal encephalopathy will have adverse outcomes.
Our current work is focussed on developing effective disease stratification tools for developing personalised neuroprotection in neonatal encephalopathy and evaluating these using quantitative MR spectroscopy biomarkers in a multi-country setting.
HELIX Trial
HELIX trial results in Lancet Global Health
Research team
Dr Sudhin Thayyil
![Dr Sudhin Thayyil](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Thayyil,-Sudhin--tojpeg_1495101446536_x4.jpg)
Dr Sudhin Thayyil
Professor of Perinatal Perinatal Neuroscience and Centre Director
Dr. Reema Garegrat
![](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/images/people-list-300X400/Dr-Reema-gargrat-751.jpg)
Dr. Reema Garegrat
Clinical Research Fellow in Neonatal Neurology
Ms Martin, Caroline J
![cpn trial manager](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/images/people-list-300X400/Caroline--trial-manager-300.jpg)
Ms Martin, Caroline J
Trial Manager for COMET
Dr Paolo Montaldo
![Dr Paolo Montaldo](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/Montaldo,-Paolo--tojpeg_1495101550069_x4.jpg)
Dr Paolo Montaldo
MRC Doctoral Research Fellow
Dr Constance Burgod
![Ms Constance Burgod](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/image001--tojpeg_1592045435400_x4.jpg)
Dr Constance Burgod
Postdoctoral researcher
Dr Vaisakh Krishnan
![Vaisakh](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/migration/research-groups/photo-2020-10-24-16-03-29_1603554563807_x4.jpg)
Dr Vaisakh Krishnan
Clinical Research Associate (PhD student)
Dr. Pallavi Muraleedharan
![](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/images/people-list-300X400/pallavi300.jpg)
Dr. Pallavi Muraleedharan
NIHR SPARK Fellow and Research Associate (PhD Student)
Mr Mahesh Javarappa
![](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/images/people-list-300X400/mahesh-300.jpg)
Mr Mahesh Javarappa
Finance Manager
Ms Harini V
![](https://pxl-imperialacuk.terminalfour.net/fit-in/428x572/filters:upscale()/prod01/channel_2/media/images/people-list-300X400/harini-300.jpg)
Ms Harini V
Data Manager